An important poem from this era San Leupphasun (Lao: ສານລຶພສູນ) discusses relations among Laos and Thailand in the veiled fashion, using the Nāga and also the Garuḍa to represent the Lao and the Thai, respectively.[fifty six] The Nāga is included thoroughly into Lao iconography, and functions prominently in Lao tradition all over the length of the nation, not simply in Vientiane.
enzyme can bind but one divalent cation from the active web page. For just a binuclear metal Middle, the activation of the amide bond as well as the activation with the solvent water is usually dispersed independently between The 2 steel ions. Nonetheless, in the mononuclear steel Heart, the two features must be borne by just one divalent cation. These benefits emphasize the numerous diversity to the evolution of functionality inside the amidohydrolase superfamily.
with several different substrate analogs. The response system is of interest considering the fact that NagA from bacterial resources is uncovered with both a couple of divalent metallic ions in the Energetic web page.
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^ Kathiragesu Indrapala writes that "From the traditions preserved inside the early Sri Lankan chronicles and also inside the early Tamil literary works the Nagas show up as a distinct group".[forty] He further more writes that "the adoption with the Tamil language was assisting the Nagas from the Tamil chiefdoms to be assimilated into the most important ethnic team there".
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Mutation of this residue to either glutamine or alanine results in mutant enzymes that have lost a substantial level of catalytic exercise. The value of k